Melperone is a so-called neuroleptic, a drug that acts on the central nervous system and can be used in various mental and neurological disorders. It belongs to a whole group of drugs with the same mechanism of action, but each one has a specific action profile.
Special action profile
In the case of neuroleptics, there are strong, medium and weak drugs. Melperon belongs to the middle group. Its effect is therefore only moderately pronounced, but the side effects are therefore also moderate. Its use is due to the relatively low side effects, especially in geriatrics, ie in the treatment of the elderly.
Effect of Melperone
Melperone is a drug that works in the brain. It occupies docking sites (receptors) for certain messenger substances (hormones) in the body and in the central nervous system. This will downregulate the effect of these messengers. Its main effect unfolds by occupying serotonin and dopamine receptors, which are located in certain parts of the brain.
Serotonin works everywhere in the body and fulfills various tasks. Among other things, it controls emotions. If too much serotonin is present in the brain, it can lead to an anxiety disorder, which is why a blockade of the serotonin receptors by Melperon has an anxiolytic effect.
Dopamine also has many different functions. Too high a level of dopamine in the brain is associated with psychotic symptoms, such as delusions and hallucinations. By blocking dopamine receptors, melperone can alleviate the symptoms. In addition, melperone has a sleep-inducing and calming effect (sedation).
Melperon helps with these symptoms
Because of its properties, melperone helps with sleep disorders, restlessness and anxiety. Illnesses that often cause these symptoms include:
- certain personality disorders
Also in the so-called alcohol elixir, in which in addition to the aforementioned complaints also confusion states occur, Melperon is used.
Melperone is mainly used in geriatrics because, in contrast to other sedative psychotropic drugs, it has no muscle-relaxing effect and thus does not increase the risk of falling for older people.
Dosage of melperone
The dosage of melperone must be determined individually by the attending physician. How many tablets the doctor prescribes, depends on the severity of the symptoms and what effect should be achieved with the drug.
In addition, the age, side-diseases and the weight of the person affected play a role. It can take a few weeks to get the full effect.
Side effects of Melperon
In addition to nausea and vomiting and occasionally allergies, low blood pressure (hypotension) and cardiac arrhythmias may occur. A side effect typical of the group of neuroleptics is the extrapyramidal motor syndrome. This causes muscle twitching, cramping and movement disorders. If these symptoms occur, Melperon must be discontinued immediately, because later in the extrapyramidal motor syndrome is no longer curable.
It is not possible to drive in the first few days after taking melperone, which is why you should consult your doctor.
Interactions of the drug
Melperon can not be combined with any other drug. Which other drugs can lead to dangerous interactions, is in the leaflet. Under no circumstances should Melperon be taken with alcohol or other neuroleptics.
Even drugs that also act in the brain, such as some sleep, sedative or painkillers, should be used with restraint. Otherwise, the effect of Melperon can be increased, which can lead to increased drowsiness, dizziness and even respiratory problems.
Contraindications to the drug
The contraindications for Melperon are varied, which is why you can take the drug only after consultation with the attending physician. Known contraindications are an allergy to the active substance butyrophenone, liver dysfunction and a so-called malignant neuroleptic syndrome in the past.
For children under 12 years Melperon is in principle not suitable. Particular caution is advised during pregnancy and during breast-feeding, as there are no studies on the use of the drug in this regard.
Instructions for taking Melperon
Melperone tablets often contain the salty form of the active ingredient, melperone hydrochloride. He belongs to the group of butyrophenones, which are derived from the opioid pethidine, a strong analgesic.
It is important to note that you should not take melperone with milk, coffee or tea together, otherwise it may form poorly soluble compounds in the digestive tract.