Tips for pen use

Thanks to its reusability, the pen is a sensible, modern alternative to insulin injections, especially for mobile diabetics and for outpatient use. With the exception of U40 insulins, most insulins are available as pre-filled cartridges for the insulin pen. The advantages of the pen are the ease of use, the insulin dose can be easily and accurately set via a dose button and does not have to be raised from a vial first. The semi-automatic insulin delivery available on some pens makes it easier for older people to receive therapy

What should be considered ...

When injected, minimal amounts of body fluid can enter the pincushion and insulin cartridge. Therefore, pincushion and insulin cartridge should always be used for one person only. Only in this way can the transmission of diseases be prevented. If the sensitive pincers are used multiple times, the damaged cannula tip will result in additional tissue injury and may thereby cause the formation of nodular nodules. Due to the delayed wound healing in diabetics, the use of an undamaged cannula is particularly important, the needle replacement after the injection, therefore, of course. Modern pen needles are very thin, sharply ground and have a lubricating film, so that the injection is painless and well tolerated. This sliding film is already worn at the first use of the needles. On used needles can also hang tissue remnants and lead to the settlement of bacteria and other germs. When reusing the needles, these pathogens can then invade the skin.

Mixing insulin suspensions

Insulin suspensions (delay and mixed insulins) must be mixed before each injection. For this, the pen with the inserted cartridge should be swiveled up and down at least 20 times. The insulin must be uniformly milky white. Only with complete mixing of insulin suspensions a uniform dosage is guaranteed. Please also note the leaflet for the insulin cartridge.

Bleeding and functional check

To ensure correct dosing, any air that may be in the insulin cartridge or accumulated during use must be removed. For ventilation and functional control it is therefore necessary to check that insulin is released from the pincushion before each injection by setting 2 IU.

Adjusting the insulin dose

Before setting the dose, it must be ensured that the dosing button is in the zero position. By turning the Dosierknopfes the desired number of insulin units can be adjusted. Depending on the pen, the setting is made in increments of 1 or 2 IE.


The attending physician decides on the type and amount of insulin injections. The injector should reassure himself that the right insulin is inserted before each injection. Check that the dosing button is in the zero position again after the injection. Wait about 5 seconds before pulling the needle out of the skin. If the dosing button stops before turning back to zero, the insulin cartridge will not contain sufficient insulin. The remaining amount of insulin indicated by the display must then still be injected after changing the insulin cartridge


Please always store the pen without a cannula to prevent the leakage of insulin and the ingress of air into the insulin cartridge. The insulin cartridge can remain in the pen. After use, replace the wing cap and place the pen back in its pocket. Protect the pen from heavy pressure, dirt, dust and extreme temperatures.


For cleaning do not use alcoholic cleaning agents. For cleaning a damp cloth is sufficient. The pen must not be immersed in water.

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