Tetrazepam is an active ingredient in the benzodiazepine group used to treat muscle tension. Benzodiazepines have a calming and anxiety-relieving effect. Because tetrazepam can make you addicted quickly, the drug is not suitable for people with acute or past alcohol, drug or drug dependence. Learn more about the side effects, dosage, contraindications and interactions of tetrazepam.
Effect of tetrazepam
Tetrazepam has been used primarily as a muscle relaxant. The active ingredient can be used to treat muscle tension caused by diseases of the spine and joints. In addition, tetrazepam was also prescribed for the treatment of pathologically increased muscle tension (spastic syndrome). The active substance may no longer be prescribed since 1 August 2013, as serious skin reactions may occur.
Side effects of tetrazepam
The most common side effects with Tetrazepam include dizziness, tiredness, drowsiness, drowsiness, articulation disorders, gait insecurity, and reduced responsiveness. In addition, gastrointestinal complaints such as diarrhea, constipation, nausea and vomiting may occur. Some of these side effects may fade during the course of treatment.
Occasionally, side effects of tetrazepam may be hypersensitivity reactions, including reddened and swollen areas of the skin and mucous membranes. Rarely, it can also lead to side effects such as dry mouth, depressive moods, drop in blood pressure, respiratory and muscle weakness and a decrease in libido after taking.
In some cases, while taking tetrazepam, reactions may occur that are in contrast to the actual effect of the substance. These reactions include, for example, sleep disorders, anxiety and tantrums. In case of such an effect reversal, which can occur especially in children and elderly persons, the treatment should be stopped.
Ingestion can make dependent
The intake of tetrazepam can already lead to addiction after a short time. Usually enough for the daily intake of a usual dose over a few weeks. Therefore, at the latest four weeks after the start of treatment by a doctor should be checked whether the use of the drug is still necessary.
If the drug is suddenly discontinued after prolonged use, severe withdrawal symptoms may occur. These may include headaches, insomnia, increased dreams, anxiety, restlessness, tremors, sweating, delusions, depression, muscle aches, tension and seizures.
In part, the withdrawal symptoms occur with a delay of a few days. You can last between a few days and a few weeks. In order to minimize the withdrawal symptoms, the drug should never be discontinued abruptly when stopping treatment with tetrazepam, but the dose should be slowly reduced.
Dosage of tetrazepam
Tetrazepam was a prescription and should only be taken after consulting a doctor. He had determined the individually optimal dosage for you. Please understand therefore the following dosage information only as a general guideline.
At the beginning of treatment, the dose is usually increased gradually until the smallest effective dose is determined. At the beginning, adults usually take 50 milligrams of tetrazepam - an increase of up to 200 milligrams is possible. In spastic syndromes can be taken in individual cases up to 400 milligrams per day.
Since you may experience memory lapses after taking tetrazepam, it is best to take the drug at bedtime in the evening. Otherwise, it may happen that you take actions after taking them that you will not be able to remember later.
If taken regularly, the effects of tetrazepam may be reduced over time. In this case, do not increase the dose on your own initiative, but consult your doctor.
In case of overdose immediately to the doctor
If you have taken too much tetrazepam, it is important to contact a doctor for evaluation of the severity of the poisoning. A slight overdose may cause side effects such as drowsiness, drowsiness, confusion, and insecurity of walking and muscle weakness. Stronger doses can lead to unconsciousness, respiratory problems and circulatory collapse.
Contraindications of tetrazepam
Tetrazepam should not be used if there is hypersensitivity to the active substance itself or to other benzodiazepine agents such as diazepam. In addition, the active ingredient may not be taken in:
- an acute or past dependence on alcohol, drugs or medications
- a serious impairment of breathing
- an acute intraocular pressure increase
- Breathing interruptions during sleep (sleep apnea syndrome)
- Children under one year
Patients with severe liver damage, impaired renal function, respiratory or muscular dysfunction (Myasthenia gravis) should be monitored carefully while taking tetrazepam. The same applies to patients suffering from acute poisoning with alcohol, analgesics, hypnotics, neuroleptics or antidepressants. Also with movement disturbances, which are caused by illnesses of brain or spinal cord, caution is necessary.
In older people, tetrazepam may break down more slowly than usual. In addition, they often react particularly sensitive to the drug. Because of this, older people must be monitored with particular care when taking tetrazepam - especially if they are in poor general condition.
Tetrazepam during pregnancy
Tetrazepam should not be taken during pregnancy or only after a careful risk-benefit assessment. Because the active ingredient can cause malformations and mental limitations in the unborn child. If the active substance is used regularly during pregnancy, in higher doses or during childbirth, the child may experience withdrawal symptoms such as flaccid muscles, difficulty breathing and dehydration.
If tetrazepam is taken during breastfeeding, it should be weaned beforehand. Because the drug passes into breast milk and is degraded much slower in infants than in adults. As a result, side effects such as dehydration or difficulty breathing may occur.
Interactions with other drugs
If Tetrazepam is taken concomitantly with certain other medications, interactions may occur.
- If tetrazepam is taken simultaneously with substances that act in the central nervous system - for example, alcohol, psychotropic drugs, opioid painkillers, sleeping pills and sedatives, and H1-antihistamines - it can lead to a mutual increase in effectiveness.
- By taking omeprazole, cisapride, cimetidine and grapefruit extracts, the effect of tetrazepam can be increased.
- Tetrazepam strengthens the effects of other muscle relaxants, resulting in increased risk of falling, especially in older people or high doses.
- The simultaneous use of tetrazepam and clozapine increases the risk of circulatory failure.
- Cholinesterase inhibitors may weaken the muscle-relaxing effect of tetrazepam.
- If tetrazepam is taken together with other active substances from the group of benzodiazepines, the danger of dependence increases.
Antihypertensives, anticoagulants, hypoglycemic agents and hormonal contraceptives should be taken with tetrazepam only after consulting a doctor. Taking it at the same time may result in unforeseen interactions.
During the first days of ingestion, driving and operating machinery should be avoided. Even later, the concentration and the reactivity can be negatively influenced by tetrazepam. The treating physician then has to decide on a case-by-case basis whether it is possible to drive vehicles and operate machines.