The active ingredient Sildenafil is used in men for the treatment of erectile dysfunction. The active substance has become known through the sexual enhancer Viagra®. It facilitates the achievement of an erection - but only if there is sexual stimulation. Otherwise sildenafil has no effect. As with many other medications, taking sildenafil can cause side effects. The most common include headache, facial flushing and gastrointestinal discomfort. Find out more about the effects, side effects and dosage of sildenafil here.
Effect of the potency agent
Sildenafil is used primarily to treat erectile dysfunction (impotence). The active ingredient ensures that an erection can be maintained longer. He has no lust-increasing effect and does not provide for an erection by itself. Rather, sildenafil improves men's ability to respond to sexual arousal with an erection. Without a sexual stimulation, however, no erection is triggered.
The drug is just like tadalafil or vardenafil to the group of PDE-5 inhibitors, which have a vasodilator effect. This effect is based on the inhibition of the enzyme phosphodiesterase-5. By inhibiting the enzyme, the blood vessels in the penis relax. This facilitates the influx of blood and the erection of an erection.
Since 2006, sildenafil has also been approved as a sexual enhancer for the treatment of pulmonary hypertension (pulmonary hypertension). Again, his vasodilator effect plays a crucial role in the treatment.
Side effects of sildenafil
As with most other medications, sildenafil intake is associated with side effects. These are usually mild to moderate and will fade away after a while. For a complete list of all side effects of the drug, please refer to the package leaflet of your medication.
After taking sildenafil, the following symptoms may occur:
- a headache
- facial flushing
- Stomach discomfort such as nausea, vomiting and diarrhea
- vision problems
- Muscle and back pain
- hearing impairment
- a lowered reaction
- a permanent erection
In very rare cases, a circulatory disorder of the optic nerve head (anterior ischemic optic neuropathy) was observed after ingestion. This can lead to permanent visual damage or even blindness. Whether the disorder is in a causal relationship with the intake of the drug is still unclear. If you are taking the medicine and have a decrease in vision, contact your doctor immediately and stop taking any more pills.
Dose sildenafil correctly
Sildenafil is available in doses of 25, 50 and 100 milligrams and is administered orally.
- Normal tablets should be swallowed whole with some liquid.
- Chewable tablets are first chewed and then swallowed.
- Orodispersible tablets are placed on the tongue and swallowed only after dissolution.
How high the dose to be taken should be with you, your doctor will determine individually. In addition to the individual effectiveness and tolerability of the drug also present underlying diseases play a role. Irrespective of this, it should never be exceeded a daily dose of 100 milligrams.
The effect of the tablet begins about 30 to 60 minutes after ingestion. A luscious, greasy meal may delay the onset of action. After the effect starts, it will last for about four to five hours.
Contraindications: Caution in coronary heart disease
Sildenafil must not be used concomitantly with medications containing nitrates and nitric oxide donors (for example, molsidomine). Otherwise, it can lead to a significant increase in the effectiveness of these drugs.
It should also be noted that patients with coronary heart disease should take the drug only after consulting their doctor. For them, the stress of intercourse can increase the risk of overuse of the circulation. Likewise, the use is contraindicated in severe liver damage and an allergy to the drug.
In addition, sildenafil should only be taken with particular care in the following conditions: leukemia, peptic ulcer, multiple myeloma, sickle cell anemia, blood clotting disorder. Likewise, if you have a disease or deformity of your penis, you should consult your doctor before taking it.
Interactions with other drugs
Taking sildenafil may result in a number of drug-drug interactions. Affected are primarily drugs that are metabolized with the participation of the same enzymes as the power means:
Interactions with alpha-blockers may also interact: in some cases, side effects such as drowsiness and dizziness have occurred. However, this can usually be prevented by increasing the time between receipts.
Generic with sildenafil
Until June 2013, the production of drugs containing sildenafil was patent-protected. Until then, only the product Viagra® was available. There is now a large selection of generics with sildenafil. These can be bought at a cheaper price but are just as effective.
But whether original or generic: All products have in common is that these are prescription and therefore can only be taken on medical advice. You usually have to bear the costs of sildenafil treatment yourself. The statutory health insurance only assumes this if the active substance is used for the treatment of pulmonary hypertension.