Opipramol is an anxiolytic and tranquilizing drug with low addictive potential, which is often prescribed to treat anxiety. Nevertheless, if you take opipramol you may experience side effects that are not insignificant. The active substance opipramol is similar in its chemical structure to the group of tricyclic antidepressants. However, it has an anxiety-relieving and soothing effect in the first place. Therefore, opipramol is commonly prescribed as an anxiolytic drug (anxiolytic) and rarely used in depression. The drug is commonly known as Insidon®. There are many generics from different manufacturers. These are then usually simply Opipramol, followed by the manufacturer name.
Effect of opipramol
Opipramol has an anxiolytic, soothing and slightly mood-enhancing effect. It is therefore well-suited for the treatment of anxiety disorders, especially Generalized Anxiety Disorder, which is characterized by free-floating, undirected fears, anxieties and concerns.
Opipramol is also approved for the treatment of somatoform disorders. Patients with a somatoform disorder suffer from physical ailments for which no physical cause can be found even after extensive medical examination. These complaints often have a psychological cause.
Opipramol: related to antidepressants
Although opipramol is chemically related to antidepressants, other substances are preferred for the treatment of depression. For example, citalopram, escitalopram, mirtazapine, sertraline, and some others are drugs that have good antidepressant properties and high tolerability. Also in the treatment of anxiety disorders these antidepressants are often used. In addition, Bezodiazepines, such as diazepam or lorazepam, are prescribed for short-term treatment of anxiety.
The advantage of opipramol over benzodiazepines is that there is no risk of opipramol dependence. The disadvantage of opipramol, however, lies in the longer Wirklatenz: While the sedative and anxiolytic effect of benzodiazepines usually sets in immediately, this effect is delayed in opipramol. In addition, there are more frequent side effects with opipramol.
Side effects of opipramol
The side effects may vary from person to person. While some people do not perceive unpleasant side effects, others suffer more from side effects. Typical side effects of Opipramol may be the following symptoms.
- dry mouth
- Allergic skin reactions
- Confusion states in older patients
- increase in weight
- Blood picture changes (rare)
Overall, the side effects of opipramol are more diverse than with other anxiolytics, such as benzodiazepines. One advantage, however, is the lower dependency risk. The discontinuation of opipramol is usually not very problematic. Nevertheless, it should be checked out. Occasionally, after discontinuation of opipramol, the original symptoms may reappear. Despite its undesirable side effects, opipramol is a valuable drug for many patients and is often prescribed.
Dosage and instructions for use
The dosage of opipramol is discussed individually with the attending physician. Depending on the severity of the disease, the dose may vary between 50 and 300 mg per day, divided into one to three receipts. Like most psychotropic drugs, opipramol does not mix well with alcohol. It reinforces its effect. Therefore, the consumption of alcohol should be avoided after taking opipramol. Even taking other sleep and sedatives at the same time may lead to undesirable interactions.
As with all medications, opipramol should be thoroughly studied before taking the package insert and should contact a doctor or pharmacist if in doubt. In the treatment of anxiety disorders, concomitant psychotherapy should always be considered to achieve a long-term improvement in anxiety.